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  • provention bio large              takeda              dr schar              immusant

    Scientific Forum  Clinical Forum
    08:15 - 08:30am Welcome remarks 08:15 - 12:30pm SNFGE French Symposium
        08:20 - 10:00am Maladie coeliaque: physiopathologie, diagnostic et traitement
    08:30 - 10:00am

    Update in celiac disease diagnosis

     08:20 - 08:40am Physiopathologie de la maladie coeliaque
    Bana Jabri
    , Chicago, United States
    08:30 - 08:50am

    Celiac disease diagnosis in adults update
    Knut E. A. Lundin, Oslo, Norway

    08:40 - 09:00am Physiopathologie des complications malignes de la maladie coeliaque
    Nadine Cerf-Bensussan
    , Paris, France
    08:50 - 09:10am

    Celiac diagnosis in children: New ESPGHAN criteria guidelines
    Riccardo Troncone, Naples, Italy

    09:00 - 09:20am Diagnostic et traitement de la maladie coeliaque
    Christophe Cellier
    , Paris, France
    09:10 - 09:30am Mass screening vs targeted screening: update
    Maria Luisa Mearin
    , Leiden, Netherlands
    09:20 - 09:40am Hypersensibilité au gluten : mythe ou réalité
    Sherine Khater
    , Paris, France
    09:30 - 09:40am

    Phospolipid profile at 4 months of age predicts the onset of celiac disease in at risk infants.
    Renata Auricchio, Naples, Italy

    09:40 - 09:50am How long should children with a first-degree coeliac relative be followed and screened?
    Ilma Korponay-Szabo, Debrecen, Hungary
    09:40 - 10:00am Diagnostic histologique des complications de la maladie coeliaque
    09:50 - 10:00am

    Mass Screening for celiac disease in school-age children: the CELI-SCREEN multicenter study.
    Elena Lionetti, Ancona, Italy

      Julie Bruneau, Paris, France
    Thierry Molina, Paris, France
    10:00 - 10:30am COFFEE BREAK
    10:30 - 12:00pm Omics approaches in celiac disease 10:30 - 12:30pm Maladies associées et nouveaux traitements
    10:30 - 11:00am

    Genetic and environmental factors driving immune response variation in humans
    Lluis Quintana-Murci, Paris, France

    10:30 - 10:50am Indication du régime sans gluten et autres régimes (FODMAPs)
    Pauline Jouet, Paris, France
        10:50 - 11:10am

    Maladie coeliaque de l'enfant: spécificités et transition
    Alain Lachaux
    , Lyon, France
    11:00 - 11:30am  Understanding celiac disease from a genetic point of view
    Iris Jonkers, Groningen, Netherlands
    11:10 - 11:30am Intolérances alimentaires chez l’enfant
    Patrick Tounian, Paris, France
    11:30 - 11:40am Independent and cumulative effects of celiac disease susceptibility loci differentially contribute to various clinical phenotypes 
    Juliana Cerqueira, Tampere, Finland
    11:30 - 11:50am Maladies hépatiques et pancréatiques et maladie coeliaque
    Jean-Marie Peron
    , Toulouse, France
     11:40 - 11:50am Kinetics and transcriptomics of gluten-specific T cells in blood after gluten challenge
    Stephanie Zuhlke, Oslo, Norway
    11:50 - 12:10pm Classification et traitement des lymphomes associés à la maladie coeliaque
    David Sibon
    , Paris, France
     11:50 - 12:00pm NMR based Metabonomics of Intestinal Mucosal Biopsies, Blood and Urine to Identify Potential Biomarker(s) for Celiac Disease
    Govind Makharia, New Delhi, India
    12:10 - 12:30pm

    Microbiote et physiopathologie de l'intestin grêle
    Philippe Marteau
    , Paris, France

    12:15 - 01:45pm Lunch & Symposium sponsored by Provention Bio 12:30 - 01:45pm  Poster Session


    12:15 - 01:45pm

    Interleukin-15 (IL-15) in celiac disease and therapeutic potential of the anti-IL-15 antibody PRV-015/AMG 714

    12:15 - 12:30pm Unmet need in celiac disease - Patients' views 
    Marilyn Geller, Los Angeles, United States
    12:30 - 12:45pm Role of interleukin 15 (IL-15) in celiac disease
    Bana Jabri, Chicago, United States
    12:45 - 01:00pm Targeting IL-15 in celiac disease (results of CELIM-NRCD-001 trial) 
    Markku Mäki, Tampere, Finland
    01:00 - 01:15pm Targeting IL-15 in refractory celiac disease (results of CELIM-RCD-002 trial)
    Christophe Cellier, Paris, France
    01:15 - 01:30pm Next steps for anti-IL-15 (PRV-015/AMG 714) as a therapeutic for celiac disease
    Francisco Leon, Washington DC, United States
    Prista Charuworn, San Francisco, United States
    01:30 - 01:45pm Q&A 
    David Sanders, Sheffield, United Kingdom

    01:45 - 03:30pm

    Pathogenesis I

    01:45 - 03:35pm

    Epidemiological and diagnostic update in CD

    01:45 - 02:10pm

    Adaptive Immunity in celiac disease: from pathogenesis to diagnosis?
    Ludvig M.Sollid, Oslo, Norway

    01:45 - 02:05pm The global village of celiac disease
    Carlo Catassi, Ancona, Italy
    02:10 - 02:35pm

    Innate immunity in celiac disease? 
    Bana Jabri, Chicago, United States

    02:05 - 02:25pm
    The Indian and Asian perspective
    Govind Makharia, New Delhi, India
    02:35 - 03:00pm

    From autoimmunity to lymphomagenesis in celiac disease
    Nadine Cerf-Bensussan
    , Paris, France

    02:25 - 02:45pm Diagnostic and biopsy strategy
    David Sanders, Sheffield, United Kingdom
    03:00 - 03:10pm

    Tissue alarmins and adaptive cytokine induce dynamic and distinct transcriptional responses in tissue-resident intraepithelial cytotoxic T lymphocytes
    Maria Zorro, Groningen, Netherlands

    02:45 - 03:05pm Antibody negative villous atrophy
    Joseph Murray, Rochester, United States
    03:10 - 03:20pm

    The intraepithelial γδ tcr repertoire is more diverse in coeliac disease patients than in healthy subjects
    Linn Eggesbo, Oslo, Norway

    03:05 - 03:20pm Making a diagnosis of celiac disease in children
    Maria Luisa Mearin, Leiden, Netherlands
    03:20 - 03:30pm

    B-cell tolerance and antibody production to the celiac disease autoantigen transglutaminase 2 (TG2)
    Fleu Du Pre, Oslo, Norway

    03:20 - 03:35pm How to organise transition for young celiac
    Carolina Ciacci
    , Salerno, Italy
    03:30 - 04:00pm COFFEE BREAK
    04:00 - 04:40pm

    Keynote lecture
    Autoimmunity: lessons from human immunodeficiencies
    Alain Fischer, Paris, France

     04:00 - 05:40pm Endoscopy and Celiac Disease
        04:00 - 04:20pm Enteroscopy and device assisted in celiac disease
    Luca Elli
    , Milano, Italy
        04:20 - 05:00pm Role of device assisted enteroscopy in celiac disease
    Sherine Khater, Paris, France
     04:40 - 6:00pm  Drink and Posters  05:00 - 05:20pm  Novel endoscopic recognition of celiac disease (magnification, NBI, BLIetc)
    Gabriel Rahmi, Paris, France
        05:20 - 05:40pm Which work-up for suspicion of malignancy in celiac disease
           Chris Mulder, Amsterdam, Netherlands
    07:00pm Speakers' dinner  
  • provention bio large              takeda              dr schar              immusant

     Scientific Forum  Clinical Forum
    08:00 - 08:40am

    Keynote Lecture:
    The interplay between genetics and environment in type I diabetes
    Mikael Knip, Helsinki, Finland

    08:00 - 09:30 am Difficult diagnosis
    08:40 - 10:30am Epidemiology & environmental triggers 08:00 - 08:15 am A patient with positive serology and normal duodenal biopsy
    Govind Makharia, New Delhi, India
     08:40 - 09:00am Natural history of celiac disease: lessons from at risk pediatric cohorts
    Daniel Agardh, Lund, Sweden
    08:15 - 08:30 am Histological uncertainties including patients with IEL only on duodenal biopsy
    Umberto Volta, Bologna, Italy
    09:00 - 09:20am Mechanistic insight into the role of microbiota in intestinal inflammation
    Harry Sokol
    , Paris, France
    08:30 - 08:45 am Difficult histological diagnosis: RCD or lymphoma ?
    Julie Bruneau, Paris, France
    09:20 - 09:40am Environmental factors: update on the role of gut microbiota in celiac disease
    Elena Verdu
    , Ontario, Canada
    08:45 - 09:00 am What to do in a patient already on a GFD ?
    Julio Bai, Buenos Aires, Argentina
    09:40 - 09:50am Metagenomic analysis of fecal virome identifies specific enteroviruses and adenoviruses as potential triggers of celiac disease autoimmunity in the TEDDY study
    Katri Lindforts
    , Tampere, Finland
    09:00 - 09:15 am Villous atrophy and negative serology or negative HLADQ2/8
    Carolina Ciacci,
    Salerno, Italy
    09:50 - 10:00am

    Gluten intake and risk of celiac disease
    Carin Andren Aronsson, Malmo, Sweden

    09:15 - 10:30 am Sponsored symposium by Dr. Schär
        09:15 - 10:30 am Patient management in gluten-related disorders: From the best diagnosis to the best diet
        09:15 - 09:25 am

    Differential diagnose in GRD: keys of a good patient management
    David Sanders, Sheffield, United Kingdom

        09:25 - 09:40 am

    A GFD is not equal to a GFD: Quality of the diet for quality of life
    Nick Trott
    , Sheffield, United Kingdom

        09:40 - 09:55 am

    Follow up of the patient: which balance for the best compliance?
    Benjamin Lebwohl
    , New-York, United States

        09:55 - 10:05 am

    Nutritional profiles compared: processed GF food and their gluten containing equivalents (or counterparts)
    Paula Crespo
    , Valladolid, Spain

        10:05 - 10:15 am

    Re-Cereal : an innovative project to improve products’ quality
    Veronica Marin
    , Trieste, Italy

        10:15 - 10:30 am Questions & Answers
    10:00 - 10:30am COFFEE BREAK
    10:30 - 12:00pm Pathogenesis II 10:45 - 12:45pm The gluten free diet beyond the gut
    10:30 - 10:50am Lessons from animal models in celiac disease
    Valerie Abadie, Chicago, United-States
    10:45 - 11:10 am State of art lecture: The gluten free diet: safe or dangerous ?
    Benjamin Lebwohl
    , New-York, United States
    10:50 - 11:10am ATI proteins, celiac disease and gluten hypersensitivity
    Detlef Schuppan, Mainz, Germany
    11:10 - 11:25 am Are there nutritional consequences of a gluten free diet?
    Nick Trott, Sheffield, United Kingdom
    11:10 - 11:30am Innovative approaches to investigate human gut immune cells in celiac disease?
    Frits Koning, Leiden, Netherlands
    11:25 - 11:40 am The gluten free diet in neurological disease
    Marios Hadjivassilliou, Sheffield, United Kingdom
    11:30 - 11:40am

    Characterisation of Clinical and Immune Reactivity to Barley and Rye Consumption in Children with Celiac Disease
    Melinda Hardy, Victoria, Australia


    11:40 - 11:50am


    11:50 - 12:00pm

    Simultaneous transcriptional characterisation and clonal inference of disease-specific plasma cells in coeliac disease
    Ida Lindeman, Oslo, Norway
    The genetic landscape of type II Refractory Celiac Disease and Enteropathy Associated T-Cell Lymphoma reveals recurrent activating mutations of the JAK1/STAT3 axis
    Sascha Cording, Paris, France

     11:40 - 12:05 pm State of the art Lecture; Assessing adherence many questions no answers?
    Julio Bai, Buenos Aires, Argentina
    12:20 - 01:35pm Lunch & Sponsored Symposium by Takeda
     12:10 - 01:45pm LUNCH & POSTER SESSION
    12:20 - 01:35pm Imagining the future: how will the celiac disease patient journey change over the next 10 years?    
    12:20 - 12:25pm

    Welcome and introduction
    Dan Leffler
    , Boston, United States

    12:25 - 12:40pm Will there be a role for endoscopy and biopsy in the diagnosis of celiac disease in 10 years?
    David Sanders
    , Sheffield, United Kingdom
    12:40 - 12:55pm Will we still be talking about the Gluten-Free diet in 2030?
    Maureen Leonard, Boston, United States
    12:55 - 01:10pm

    Will novel technologies revolutionise the way we monitor celiac disease?
    Luca Elli, Milano, Italy

    01:10 - 01:30pm Panel discussion and Q&A    
    01:30 - 01:35pm
    Summary and close
    Dan Leffler, Boston, United States
     01:45 - 03:15pm Refractory celiac disease, non celiac disease enteropathies & intestinal lymphomas 01:45 - 03:15 pm Non-celiac gluten sensitivity & IBS and IBD
     01:45 - 02:00pm Diagnosis and treatment of non responsive celiac disease
    Christophe Cellier, Paris, France 
    01:45 - 02:05pm State of the Art Lecture: How the microbiome will change our practice ?
    Harry Sokol, Paris, France
    02:00 - 02:15pm Diagnosis and treatment of refractory celiac disease
    Chris Mulder, Amsterdam, Netherlands 
    02:05 - 02:25pm Update on pathogenesis of NCGS
    Knut E A Lundin, Oslo, Norway
    02:15 - 02:35pm Non celiac disease associated enteropathies and lymphomas
    Joseph Murray, Rochester, United States 
    02:25 - 02:45pm  IBS GFD and FODMAPs
    Sherine Khater, Paris, France
    02:35 - 02:55pm New classification of T intestinal cell lymphoma and targeted treatments
    Olivier HermineParis, France
    02:45 - 03:00pm  NGCS, Celiac disease and IBS: how to differentiate ?
    Umberto Volta, Bologna, Italy
    02:55 - 03:05pm Non-responsive and Refractory Coeliac Disease: The Largest UK Experience from the NHS England Rare Diseases Collaborative Network
    Hugo Penny, Sheffiel, United Kingdom
    03:05 - 03:15pm Characterization of a large cohort of children with non-celiac auto-immune enteropathies
    Fabienne Charbit-Henriton, Paris, france
    03:15 - 03:45pm COFFEE BREAK                              03:00 - 03:45
    03:45 - 05:05pm The spectrum of gluten associated diseases
    03:45 - 05:00pm New developments in celiac disease
    03:45 - 04:05pm Gluten hypersensitivy: myth and reality?
    Peter Green, New-York, United States
    03:45 - 04:05pm How to organize a celiac disease center ?
    Chris Mulder, Amsterdam, Netherlands
    04:05 - 04:25pm Has gluten recently changed in composition or processing ? The agronomist's view
    Katharina Scherf
    , Freising, Germany
    04:05 - 04:20pm Do adult celiac patients need Vitamin D supplementation ?
    Carolina Ciacci, Salerno, Italy
     04:25 - 04:45pm Extraintestinal manifestations of celiac disease or celiac disease associated diseases
    Jonas Ludvigsson, Stockholm, Sweden
    04:20 - 04:40pm Prevention of celiac disease: Is it possible ?
    Riccardo Troncone, Naples, Italy
    04:45 - 04:55pm Post-Mortem Immuno-Pathological Findings in the Cerebellum of Celiac Disease patients with concomitant Idiopathic Neurological Disorders
    Maxine-Dominique Rouvroye, Amsterdam, Netherlands
    04:40 - 05:00pm Round table : The evolving role of patient advocacy groups
    Heidi Urwin, Buckinghamshire, United Kingdom
    Christel Turcat, Paris, France
    Tunde Koltai, Brussels, Belgium
    Hilary Croft, Bucks, United Kingdom

    04:55 - 05:05pm IgA anti-tTG co-localization for identification of Celiac Associated Liver Diseases
    Prasenjit Das, Delhi, India
    05:05 - 06:00pm Drink & Posters  
    05:30 - 06:30pm ICDS business meeting  
    Gala Dinner  
  • provention bio large              takeda              dr schar              immusant

     Scientific Forum

    08:00 - 09:30am 

    Novel development for diagnosis and follow-up of celiac disease

    08:00 - 08:40am

    Round table: Which biomarkers to use in 2019?
    Markku Mäki, Tampere, Finland
    Govind Makharia, New Delhi, India
    Topic Introduction, where do we need biomarkers
    Markku Mäki, Tampere, Finland
    Classification of biomarkers, and non-immunological biomarkers
    Govind Makharia, New Delhi, India
    Serum antibodies as biomarkers
    Ilma Korponay-Szabo, Debrecen, Hungary
    Immunological biomarkers
    Ludvig M.Sollid, Oslo, Norway
    Angel Cebolla
    , Seville, Spain
    Lipids to predict onset of CD
    Renata Auricchio, Naples, Italy
    Biomarkers for refractory type II celiac disease
    Discussion and interaction with Audience


    08:40 - 08:55am Food safety with the GFD and benefit of nutritional support?
    Benjamin Lebwohl
    , New-York,United States
    08:55 - 09:10am Gluten diet in 2019? Unmet needs?
    Nick Trott
    , Sheffield, United Kingdom
    09:10 - 09:30am Round table: Gluten diet in 2019? Unmet needs?
    Umberto Volta
    , Bologna, Italy
    Knut E. A. Lundin
    , Oslo, Norway
    Psychological issues
    Carolina Ciacci, Salerno, Italy
    IBS-like symptoms, nutritional deficiencies and metabolic syndrome
    Luca Elli, Milano, Italy
    Educational training in newly diagnosed celiacs
    David Sanders, Sheffield, United Kingdom
    Non dietary therapies
    Peter Green, New-York, United States

    09:30 - 10:00am COFFEE BREAK
    10:00 - 10:50am Immunotherapy sponsored by Immusant
    10:00 - 10:30am Immunotherapy antigen-specific in autoimmune diseases
    David Wraith
    , Birmingham, United Kingdom
    10:30 - 10:50am Immunotherapy in celiac disease
    Bob Anderson, Cambridge, United States
    10:50 - 11:55am New development in the treatment of celiac disease

    10:50 - 11:15am

    New therapies for celiac disease : overview
    Chaitan Khosla, Stanford, United States
    11:15 - 11:25am

    Tolerogenic Immune-Modifying Nanoparticles Containing Gliadin Restore Tolerance and Abrogate Disease in Murine Models of Coeliac Disease
    Tobias Freitag
    , Helsinki, Finland

    11:25 - 11:35am Absence of clinical symptoms and negative serological tests could not predict gut mucosal recovery in celiac patients. Correlation of gut mucosal damage with the presence of urine gluten peptides
    Angel Cebolla-Ramirez,Seville, Spain
    11:35 - 11:55am Round table : the future of new therapies
    Chaitan Khosla, Stanford, United States
    Dan Leffler, Boston, United States
    Detlef Schuppan, Mainz, Germany
    Christophe Cellier, Paris, France
    11:55 - 12:15pm Sum up of the congress
    Joseph Murray, Rochester, United States

      Prizes for posters and oral communication/Conclusion